Prominence Burn appears to be the most powerful technique in Endeavor's arsenal. Endeavor uses the full might of his flames to emit a concentrated beam of heat from his body that is used to vaporize his target.
This move is so potent that it completely overpowered Hood's Super Regeneration Quirk. The powerful Nomu only survived the initial attack by moving its head out of range of the attack. However, Nomu was completed incinerated the second time Endeavor landed the attack at point-blank range.
Endeavor uses this move once again, during his fight with Tomura Shigaraki, trying to finish him off. This leaves him completely burned. Before he ends up being killed though, the villain skewers Endeavor with Rivet Stab to make him stop.
Prominence Burn appears to be Endeavor's ultimate technique that he wishes to pass down to his sons Toya and Shoto.  This goal is only partially fulfilled, as Toya, who is now Dabi, was shown to know the Super Move, but was interrupted by Best Jeanist before he could use it.