Kyudai Garaki/Relationships

All For One
Daruma is a loyal supporter of All For One being with him for at least a decade as he is seen with All For One and a young Tomura Shigaraki. Daruma uses his talents as a doctor to help rebuild All For One's body after his battle with All Might. He also creates Nomu as well as searches for Quirks for All For One to use. All For One is the only one that Daruma entrusts with his 'children' (Nomu) and the knowledge of his appearance.

Tomura Shigaraki
Daruma was present when All For One rescued and adopted Tomura as an apprentice. It was he who gave Tomura the amputated hands of his family.

Daruma does not hesitate to tell Tomura that he is still inexperienced, pointing out he has been spoiled by Kurogiri and that, for all the support he and All For One have given to him, Tomura still hasn't accomplished anything notable. However, out of loyalty to All For One, Daruma accepts Tomura as the new leader of the League of Villains and admits he is willing to provide his services to him. He is especially impressed by the willingness and desire of Tomura to destroy society.

After Tomura accomplishes his goal, he contacts Daruma and the doctor notes on how Tomura exceeded his expectations with his regaining his memory, his recent victory and the benefits it acquired, and taming Gigantomachia and agrees to aid him.

Gigantomachia
Daruma was left in charge of controlling and monitoring Gigantomachia after All For One decided to hide him after foreseeing his inevitable downfall.

Daruma knows that Gigantomachia is extremely violent and loyal to a fault to All For One, and therefor controls him with recordings of his master's voice on the radio that Gigantomachia carries on his neck. Daruma at times refers to Gigantomachia as "Machia". Daruma believes Gigantomachia is useful to Tomura's goals and refuses to lend his full support until Tomura gets Gigantomachia to submit.